“CONGRATULATIONS! You are pregnant!” This was exciting news for 27-year-old Ayesha (not her real name), who could not wait to share it with her husband and family members. It was her first pregnancy, and she was eagerly looking forward to the birth of her child.

Ayesha was booked for antenatal visits. Antenatal checkups are routinely carried out for every pregnant mother three to four times during the entire duration of her pregnancy, to assess the health of both the mother and her baby. In July 2022, Unicef figures showed that South Asia (including Pakistan), in stark contrast with the industrialised countries, showed the lowest level of antenatal care — and that barely half of the pregnant women in the region received antenatal care.

During one of her routine antenatal visits, Ayesha was diagnosed with ‘pregnancy-induced hypertension’, or what is commonly known as PIH. She was too young to have this disease, and many questions floated in her mind, about herself and her baby and what adversities future events might hold.

Pregnancy-induced hypertension is defined as high blood pressure in pregnant women, detected after 20 weeks of gestation, and a sustained blood pressure of more than140mmHg systolic and 90mmHG (or above) diastolic. A population-level analysis in 2019 has shown the prevalence of PIH in 9.3 per cent of pregnant women in Pakistan. It is a condition that is associated with higher maternal mortality and morbidity (complications).

Untreated PIH can lead to the death of the mother and her unborn baby.

The complications include pre-eclampsia that presents itself as high blood pressure, protein in the urine and signs of organ damage. There are also more severe conditions, such as eclampsia, when because of very high blood pressure, the expecting mother suffers neurological complications that can include seizures and even coma. Untreated, it can lead to the death of both the mother and her unborn baby.

With early diagnosis, PIH is treatable. Women develop this condition because of the many changes happening within their body during pregnancy. Once the diagnosis is confirmed, they are required to have medical treatment to lower their blood pressure and prevent complications from arising.

They may recover completely after giving birth or they may continue to have the problem after delivery — chronic high blood pressure, recurrence of PIH in future pregnancies, and developing early cardiovascular disease. Long-term surveillance is advised for these patients to identify whether they are recovering or their condition is persisting. The surveillance is best done by a physician, with active follow-up from the patient.

Pregnancy is a stress test of a mother’s heart. When a woman is pregnant, her heart must work 20pc to 30pc more to fulfil her body’s needs. Her heart rate increases and so does her heart function, especially in the last three months of pregnancy. A healthy heart can tolerate these changes without compromising the health of the mother or child.

However, when the mother already has heart disease or develops a cardiovascular condition during pregnancy, such as PIH, the game changes. The heart, then, struggles to perform well at the expense of the health of the mother and child. Therefore, the key to good outcomes is early diagnosis during routine antenatal checkups by primary obstetricians, and early referral to cardiovascular experts. These women may need to be taken care of in health facilities where maternal and newborn child emergency care is available.

Dr Pamela S. Douglas, a professor of cardiology at Duke University in the US, has noted: “It is important that in the cardiovascular risk assessment of women, a history of any past pregnancy-related complications like PIH or gestational diabetes should be noted as these conditions pose a sex-specific cardiovascular risk for women. In addition, children born to these mothers are at risk of developing premature cardiovascular diseases and its risk factors.”

Pregnancy is a ‘one body, two heart’ situation. There is a dire need of assessing the quality of care that pregnant women receive and their cardiovascular risk. Heart checkups before conceiving and after-delivery follow-ups for women whose pregnancy has been complicated by heart disease need to be prioritised. Once we identify our challenges, we can develop a model of care for pregnant mothers and implement it at a national level to improve maternal outcomes.

The writers are cardiologists at the Aga Khan University Hospital, Karachi. The research reported in this publication was supported by the Fogarty International Center of the National Institutes of Health under Award Number D43TW011625. The content is solely the responsibility of the writers.

Published in Dawn, December 19th, 2022

Opinion

Editorial

Judiciary’s SOS
Updated 28 Mar, 2024

Judiciary’s SOS

The ball is now in CJP Isa’s court, and he will feel pressure to take action.
Data protection
28 Mar, 2024

Data protection

WHAT do we want? Data protection laws. When do we want them? Immediately. Without delay, if we are to prevent ...
Selling humans
28 Mar, 2024

Selling humans

HUMAN traders feed off economic distress; they peddle promises of a better life to the impoverished who, mired in...
New terror wave
Updated 27 Mar, 2024

New terror wave

The time has come for decisive government action against militancy.
Development costs
27 Mar, 2024

Development costs

A HEFTY escalation of 30pc in the cost of ongoing federal development schemes is one of the many decisions where the...
Aitchison controversy
Updated 27 Mar, 2024

Aitchison controversy

It is hoped that higher authorities realise that politics and nepotism have no place in schools.